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Research peptide

BPC-157: what it is, research and calculator

BPC-157 explained in plain English: what it is, what the research shows, side effects, legal status and dosage, plus a calculator for syringe units. There is no validated human dose, and this page doesn't invent one. Also called Body Protection Compound-157, PL 14736.

BPC-157 is not approved for human use by the FDA or any other regulator. This page is educational; talk with a qualified healthcare professional before using any substance.

Calculate
Vial unit

= 5,000 mcg

mL
Dose unit
Syringe type
Syringe size

Units to draw

–units

Enter your dose.

Syringe, no result yetU-100, 1 mL syringe holding up to 100 units. Enter your dose.0102030405060708090100

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What is BPC-157?

BPC-157 is a synthetic peptide made of 15 amino acids. It was first described in 1993 by researchers who based it on a protein found in human gastric juice, and its name stands for “Body Protection Compound.”

It is sold as a white powder in a sealed vial, most often 5 mg or 10 mg, and has to be mixed with bacteriostatic water before use. That mixing step is where the math above comes in.

What does the research on BPC-157 show?

Almost all of the research on BPC-157 is in animals and cells, not people. Studies in rats and mice have looked at tendons, muscles, ligaments, bones and the gut, often with positive results.

Human evidence is very limited. A 2025 review found only three small published pilot studies, with between 2 and 16 people each: one on knee pain, one on bladder pain (interstitial cystitis) and one on safety when given into a vein. None was a large controlled trial. The review’s authors concluded that BPC-157 should not be recommended for clinical use until well-designed human trials are done.

Researchers have also raised possible risks that haven’t been studied in people, including effects on blood vessel growth. Products sold online as “research chemicals” are not checked for purity or labeling.

BPC-157 is not approved for human use by the FDA or by any other regulator. Its rules for pharmacy compounding in the US changed in 2026:

  • FDA concerns: the FDA has said compounded BPC-157 may carry a risk of immune reactions and impurities, and that it lacks enough safety information to know whether it causes harm in people.
  • April 2026: the nominations for BPC-157 were withdrawn, so it moved off the FDA’s list of compounding substances with safety concerns (Category 2). That is not an approval.
  • July 2026: an FDA advisory committee voted to recommend adding BPC-157 to the list of substances pharmacies may compound. The vote is advisory only; the FDA still has to decide, and pharmacies can’t compound it under that list until it does.
  • Sport: the World Anti-Doping Agency bans BPC-157 at all times, so athletes who are tested can’t use it.

Laws differ between countries and change over time. Check the rules where you live.

How do you reconstitute BPC-157?

You mix the powder with bacteriostatic water, then use the calculator to turn your dose into syringe units. The step-by-step method is the same for any peptide vial: see how to reconstitute peptides, and choosing how much water to add for picking an amount of water.

This site gives no dose for BPC-157. The dose you enter should come from a qualified healthcare professional.

BPC-157 dosage

BPC-157 has no approved or validated human dose. The three small human pilot studies used different routes and amounts in 2 to 16 people, far too few to show what is safe or effective.

There is no approved or validated human dose. This site does not repeat doses from forums, sellers or animal studies.

Medical disclaimer: this dosage information is for education only and comes from the source shown for each row. It is not medical advice and not a recommendation for you. Only a licensed prescriber who knows your health can decide whether BPC-157 is right for you and at what dose. Don't start, change or stop a medicine based on this page, and don't use research peptides or unapproved drugs based on trial doses.

BPC-157 concentration chart

The concentration of a BPC-157 vial depends only on its size and the water you add. Each unit on a U-100 syringe holds one hundredth of a mL.

BPC-157 concentration by vial size and water
Vial + waterConcentrationPer unit (U-100)
5 mg + 1 mL5,000 mcg/mL (5 mg/mL)50 mcg per unit (0.05 mg per unit)
5 mg + 2 mL2,500 mcg/mL (2.5 mg/mL)25 mcg per unit (0.025 mg per unit)
5 mg + 3 mL1,666.67 mcg/mL (1.66667 mg/mL)16.67 mcg per unit (0.01667 mg per unit)
10 mg + 1 mL10,000 mcg/mL (10 mg/mL)100 mcg per unit (0.1 mg per unit)
10 mg + 2 mL5,000 mcg/mL (5 mg/mL)50 mcg per unit (0.05 mg per unit)
10 mg + 3 mL3,333.33 mcg/mL (3.33333 mg/mL)33.33 mcg per unit (0.03333 mg per unit)

Frequently asked questions

How much water do I add to a BPC-157 vial?

There is no single right amount; it depends on the units you want each dose to take. With 2 mL in a 5 mg vial, the mix is 2,500 mcg per mL, or 25 mcg per unit on a U-100 syringe. The bacteriostatic water calculator works out the water for any number of units.

Does this calculator tell me what dose of BPC-157 to use?

No. It only does the math for a dose you enter. BPC-157 has no approved dose, and this site never suggests one; talk with a qualified healthcare professional.

Is BPC-157 FDA approved?

No. BPC-157 is not approved by the FDA, or by any other regulator, for use in people. In 2026 an FDA advisory committee recommended allowing it in compounding, but that vote is not binding.

Is BPC-157 banned in sport?

Yes. The World Anti-Doping Agency prohibits BPC-157 at all times under section S0, non-approved substances.

Sources

  1. McGuire et al. (2025), Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing, Current Reviews in Musculoskeletal Medicine
  2. FDA, Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks
  3. FDA, July 23-24, 2026 Meeting of the Pharmacy Compounding Advisory Committee
  4. USADA, BPC-157 - Experimental Peptide Creates Risk for Athletes
  5. Sport Integrity Australia, BPC-157

Last updated .

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