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Research peptide

What is 5-amino-1MQ?

5-Amino-1MQ explained in plain English: what it is, what the research shows, side effects, legal status and dosage. There is no validated human dose, and this page doesn't invent one. Also called 5-amino-1-methylquinolinium, NNMT inhibitor.

5-Amino-1MQ is not approved for human use by the FDA or any other regulator. This page is educational; talk with a qualified healthcare professional before using any substance.

What is 5-amino-1MQ?

5-Amino-1MQ is a small lab-made molecule that blocks an enzyme called NNMT (nicotinamide N-methyltransferase). It was developed at the University of Texas Medical Branch.

It is not a peptide, though peptide sellers often sell it as capsules or powder alongside peptides.

What does 5-amino-1MQ do?

NNMT is especially active in fat tissue, where it uses up building blocks the body needs to make NAD+. Blocking it is thought to raise NAD+ in fat cells and make them burn more energy.

What does the research on 5-amino-1MQ show?

In a 2018 study, mice made obese with a high-fat diet lost fat and weight on 5-amino-1MQ without eating less, and their blood sugar control improved. The research since has stayed in animals and cells.

There are no human trials, so its effects and safety in people are unknown.

5-Amino-1MQ side effects and risks

Its side effects in people are unknown. Products sold online aren’t checked for purity, strength or identity.

5-Amino-1MQ is not approved for human use by the FDA or any other regulator, and it is not a legal dietary supplement ingredient.

5-Amino-1MQ dosage

5-Amino-1MQ has only been tested in mice, so there is no validated human dose.

There is no approved or validated human dose. This site does not repeat doses from forums, sellers or animal studies.

Medical disclaimer: this dosage information is for education only and comes from the source shown for each row. It is not medical advice and not a recommendation for you. Only a licensed prescriber who knows your health can decide whether 5-Amino-1MQ is right for you and at what dose. Don't start, change or stop a medicine based on this page, and don't use research peptides or unapproved drugs based on trial doses.

Frequently asked questions

Is 5-amino-1MQ a peptide?

No. It is a small molecule, not a chain of amino acids. It is sold by peptide sellers, which is why it is often grouped with peptides.

Does 5-amino-1MQ cause weight loss?

In mice on a high-fat diet it reduced fat and body weight. It has not been tested in people.

Is 5-amino-1MQ legal?

It is not approved for human use and is sold as a research chemical.

Sources

  1. Neelakantan et al. (2018), Selective and membrane-permeable small molecule inhibitors of NNMT reverse high fat diet-induced obesity in mice, Biochemical Pharmacology (UTMB listing)

Last updated .

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