Skip to content
Easy Peptide Info
Menu
Research peptide

What is AOD-9604?

AOD-9604 explained in plain English: what it is, what the research shows, side effects, legal status and dosage, plus a calculator for syringe units. There is no validated human dose, and this page doesn't invent one. Also called AOD 9604, HGH fragment 177-191.

AOD-9604 is not approved for human use by the FDA or any other regulator. This page is educational; talk with a qualified healthcare professional before using any substance.

Calculate
Vial unit

= 5,000 mcg

mL
Dose unit
Syringe type
Syringe size

Units to draw

–units

Enter your dose.

Syringe, no result yetU-100, 1 mL syringe holding up to 100 units. Enter your dose.0102030405060708090100

Saved calculations

No saved calculations yet. Save one from the results.

What is AOD-9604?

AOD-9604 is a lab-made peptide copied from the tail end of human growth hormone, the part thought to help break down fat. It was developed in Australia in the 1990s and 2000s as an anti-obesity drug.

It was designed to keep growth hormone’s fat-burning effect without its effects on growth, blood sugar or IGF-1.

What is AOD-9604 used for?

It is sold online for fat loss, and sometimes promoted for joint and cartilage repair. Neither use is approved.

What does the research on AOD-9604 show?

Early results were encouraging: in rodents it reduced fat, and a 12-week human trial reported slightly more weight loss than placebo. But the larger 24-week trial in 536 people found no meaningful weight loss compared with placebo, and development as an obesity drug ended in 2007.

There are no good human trials showing it helps fat loss or joint repair.

AOD-9604 side effects and risks

In the human trials, AOD-9604 was generally well tolerated. Its long-term effects aren’t known, and the FDA has noted a possible risk of immune reactions.

Products sold online aren’t checked for purity or strength.

AOD-9604 is not approved as a medicine by the FDA or any other regulator. In 2024 it moved off the FDA’s list of compounding substances with safety concerns after its nomination was withdrawn, which is not an approval.

It is banned in sport under the World Anti-Doping Agency’s rule for unapproved substances.

How do you reconstitute AOD-9604?

AOD-9604 comes as a powder that is mixed with bacteriostatic water. The calculator above turns the vial size, the water and a dose into syringe units, and the reconstitution guide explains each step.

See the dosage section below for what is known about doses, with sources.

AOD-9604 dosage

AOD-9604 has no approved dose. It failed its main weight loss trial, and development stopped, so there is no validated dose for any use.

There is no approved or validated human dose. This site does not repeat doses from forums, sellers or animal studies.

Medical disclaimer: this dosage information is for education only and comes from the source shown for each row. It is not medical advice and not a recommendation for you. Only a licensed prescriber who knows your health can decide whether AOD-9604 is right for you and at what dose. Don't start, change or stop a medicine based on this page, and don't use research peptides or unapproved drugs based on trial doses.

AOD-9604 concentration chart

The concentration of a AOD-9604 vial depends only on its size and the water you add. Each unit on a U-100 syringe holds one hundredth of a mL.

AOD-9604 concentration by vial size and water
Vial + waterConcentrationPer unit (U-100)
2 mg + 1 mL2,000 mcg/mL (2 mg/mL)20 mcg per unit (0.02 mg per unit)
2 mg + 2 mL1,000 mcg/mL (1 mg/mL)10 mcg per unit (0.01 mg per unit)
2 mg + 3 mL666.67 mcg/mL (0.66667 mg/mL)6.67 mcg per unit (0.00667 mg per unit)
5 mg + 1 mL5,000 mcg/mL (5 mg/mL)50 mcg per unit (0.05 mg per unit)
5 mg + 2 mL2,500 mcg/mL (2.5 mg/mL)25 mcg per unit (0.025 mg per unit)
5 mg + 3 mL1,666.67 mcg/mL (1.66667 mg/mL)16.67 mcg per unit (0.01667 mg per unit)

Frequently asked questions

Does AOD-9604 work for weight loss?

Not in its main human trial. A 24-week study in 536 people found no meaningful weight loss compared with placebo, and development as an obesity drug was stopped in 2007.

Is AOD-9604 the same as HGH fragment 176-191?

They're closely related. Both are the tail end of human growth hormone; AOD-9604 has an extra amino acid added to make it more stable.

Is AOD-9604 banned in sport?

Yes. Anti-doping agencies treat it as a prohibited substance under the World Anti-Doping Agency's rule for unapproved drugs.

Sources

  1. Misra (2013), Central and Peripheral Molecular Targets for Anti-Obesity Pharmacotherapy (reports the AOD-9604 phase 2b result)
  2. FDA, Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks
  3. World Anti-Doping Agency, The Prohibited List

Last updated .

More peptide guides and calculators