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What is GHRP-2 (pralmorelin)?

GHRP-2 explained in plain English: what it is, what the research shows, side effects, legal status and dosage, plus a calculator for syringe units. There is no validated human dose, and this page doesn't invent one. Also called Pralmorelin, KP-102.

GHRP-2 (pralmorelin) is approved in Japan only as a one-time diagnostic test, and not by the FDA. This page is educational; talk with a qualified healthcare professional before using any substance.

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= 5,000 mcg

mL
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Syringe, no result yetU-100, 1 mL syringe holding up to 100 units. Enter your dose.0102030405060708090100

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What is GHRP-2?

GHRP-2 is a lab-made peptide of six amino acids that makes the pituitary gland release growth hormone. Its drug name is pralmorelin.

It copies ghrelin, the “hunger hormone”, at the receptor that triggers growth hormone release. In Japan it has been approved since 2004 as a one-time diagnostic test for growth hormone deficiency.

What does GHRP-2 do?

GHRP-2 causes a strong, short pulse of growth hormone. It also raises cortisol and prolactin somewhat, and increases appetite, though less than GHRP-6.

People use it hoping for muscle, fat loss and recovery, often with a GHRH peptide like CJC-1295. See growth hormone peptides for how the two types differ.

What does the research on GHRP-2 show?

Research confirms GHRP-2 reliably raises growth hormone, which is why Japan uses it to test the pituitary. There are no good trials showing it builds muscle, burns fat or slows aging in healthy adults.

GHRP-2 side effects and risks

Reported side effects include hunger, flushing, water retention, tingling and higher blood sugar. Raising cortisol and prolactin over time may cause problems of its own.

The FDA has flagged possible immune reactions, and products sold online aren’t checked for purity or strength.

GHRP-2 is approved only in Japan, as a diagnostic, and not by the FDA. In the US it is on the FDA’s list of compounding substances with safety concerns for outsourcing facilities, and it is banned in sport at all times.

How do you reconstitute GHRP-2?

GHRP-2 research vials hold a freeze-dried powder that is mixed with bacteriostatic water. The calculator above turns the vial size, the water and a dose into syringe units, and the reconstitution guide explains each step.

See the dosage section below for what is known about doses, with sources.

GHRP-2 dosage

GHRP-2 has no approved treatment dose anywhere. In Japan it is given once, by IV, as a diagnostic test under medical supervision, which is not a treatment dose.

There is no approved or validated human dose. This site does not repeat doses from forums, sellers or animal studies.

Medical disclaimer: this dosage information is for education only and comes from the source shown for each row. It is not medical advice and not a recommendation for you. Only a licensed prescriber who knows your health can decide whether GHRP-2 is right for you and at what dose. Don't start, change or stop a medicine based on this page, and don't use research peptides or unapproved drugs based on trial doses.

GHRP-2 concentration chart

The concentration of a GHRP-2 vial depends only on its size and the water you add. Each unit on a U-100 syringe holds one hundredth of a mL.

GHRP-2 concentration by vial size and water
Vial + waterConcentrationPer unit (U-100)
5 mg + 1 mL5,000 mcg/mL (5 mg/mL)50 mcg per unit (0.05 mg per unit)
5 mg + 2 mL2,500 mcg/mL (2.5 mg/mL)25 mcg per unit (0.025 mg per unit)
5 mg + 3 mL1,666.67 mcg/mL (1.66667 mg/mL)16.67 mcg per unit (0.01667 mg per unit)
10 mg + 1 mL10,000 mcg/mL (10 mg/mL)100 mcg per unit (0.1 mg per unit)
10 mg + 2 mL5,000 mcg/mL (5 mg/mL)50 mcg per unit (0.05 mg per unit)
10 mg + 3 mL3,333.33 mcg/mL (3.33333 mg/mL)33.33 mcg per unit (0.03333 mg per unit)

Frequently asked questions

What is GHRP-2 used for?

In Japan it is a one-time diagnostic test for growth hormone deficiency. Online it is sold to raise growth hormone for muscle and fat loss, uses that are not approved.

What is the difference between GHRP-2 and GHRP-6?

Both act on the ghrelin receptor. GHRP-2 is more potent for growth hormone and causes less hunger than GHRP-6.

Is GHRP-2 banned in sport?

Yes. The World Anti-Doping Agency bans growth hormone secretagogues like GHRP-2 at all times.

Sources

  1. Wikipedia, Pralmorelin (with cited studies)
  2. FDA, Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks
  3. World Anti-Doping Agency, The Prohibited List

Last updated .

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