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What is oxytocin?

Oxytocin explained in plain English: what it is, what the research shows, side effects, legal status and dosage. Doses shown come only from the label or published trials, each with its source. Also called Pitocin, Love hormone.

Oxytocin (Pitocin) is a prescription medicine given in hospitals during and after childbirth. Oxytocin nasal sprays sold for mood or bonding are not approved. This page is educational; talk with a qualified healthcare professional.

What is oxytocin?

Oxytocin is a natural hormone of nine amino acids, made in the brain’s hypothalamus and released by the pituitary gland. It is best known for its roles in childbirth and breastfeeding.

A lab-made version, Pitocin, is a prescription medicine used in hospitals.

What does oxytocin do?

Oxytocin makes the womb contract during labor and helps release milk during breastfeeding. It is also released during touch and sex and acts in the brain on trust, bonding and stress, which is why it is called the “love hormone”.

What is oxytocin used for medically?

Pitocin is FDA-approved to start or strengthen labor contractions and to control bleeding after childbirth. It is given only in hospitals, by IV drip or injection, with close monitoring of the mother and baby.

Do oxytocin nasal sprays work?

Not reliably. A large 2021 trial in children and teens with autism found oxytocin nasal spray didn’t improve social skills, and studies on anxiety, relationships and weight have mixed results.

Nasal sprays are sold online for mood, bonding and libido, but they aren’t approved for those uses.

Oxytocin side effects and risks

In hospital use, too much oxytocin can cause overly strong contractions that stress the baby, and very high amounts can cause water retention and low sodium. Nasal sprays bought online may not contain what the label says.

Oxytocin is a prescription drug in the US, approved only for hospital use in childbirth. Oxytocin products sold online for other uses are not approved.

Oxytocin dosage

Pitocin is given only in hospitals, by IV drip with an infusion pump, and the rate is adjusted to the contractions by the medical team. These label rates are not for use at home.

From the official prescribing information (label). Your prescriber decides your dose and when to change it.

Oxytocin doses, with sources
WhenDoseHow often
Labor induction, starting rate (IV drip)0.5 to 1 milliunit per minute[1]Continuous infusion
Labor induction, increases1 to 2 milliunits per minute[1]Every 30 to 60 minutes until a normal labor pattern
  1. Drugs.com, Pitocin dosage guide (from the label)

Medical disclaimer: this dosage information is for education only and comes from the source shown for each row. It is not medical advice and not a recommendation for you. Only a licensed prescriber who knows your health can decide whether Oxytocin is right for you and at what dose. Don't start, change or stop a medicine based on this page, and don't use research peptides or unapproved drugs based on trial doses.

Frequently asked questions

Why is oxytocin called the love hormone?

Because it is released during touch, sex, childbirth and breastfeeding, and animal studies link it to bonding. The real picture in people is more complicated.

Do oxytocin nasal sprays work?

Not reliably. A large 2021 trial in children with autism found no benefit on social skills, and results for anxiety and relationships are mixed.

Is oxytocin nasal spray legal?

Oxytocin is a prescription drug in the US, approved only for hospital use in childbirth. Nasal sprays sold online for mood or bonding are not approved.

Sources

  1. DailyMed, Pitocin (oxytocin injection) prescribing information
  2. Sikich et al. (2021), Intranasal Oxytocin in Children and Adolescents with Autism, NEJM

Last updated .

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